Picks ranked outside of the first 10 rounds (121+ overall) that have chance of being usable in fantasy.
125. Victor Cruz, WR
Cruz's fantasy point totals over his 4 year career: 205, 169, 121, and 37 (he completed just 5 games last season). Even at his worst in 2013, Cruz was at least a flex play and his current rank as the 52nd wide receiver is well outside of flex territory. Eli Manning is good enough to sustain two fantasy-relevant wide receivers and the schedule is favorable. To those that say Cruz is less valuable playing second fiddle to OBJ, I'd like to point out that Cruz was the #2 on the Giants in 2011 and 2012, his best years by a wide margin.
135. Eddie Royal, WR
With rookie Kevin White possibly out for the season and Alshon Jeffery limping in camp, Eddie Royal might have lucked into a lucrative role. For all his faults, Jay Cutler has consistently gotten big numbers out of Brandon Marshall and Alshon Jeffery. Eddie Royal has a combined 15 touchdowns in the past two seasons.
136. David Johnson, RB
Andre Ellington doesn't have the frame to handle feature back duties in Arizona. David Johnson does.
145. Delanie Walker, TE
Finished 9th among TEs last season and gets a sizable upgrade at QB in Marcus Mariota. Why take Jason Witten at #81 when you can get Delanie Walker who outscored him in 2014 and will likely do so again in 2015?
150. Eli Manning, QB
He finished as the 10th best QB in 2014. He gets Odell Beckham Jr. for a full season, a healthy Victor Cruz, and the newly acquired WR James Jones and pass-catching RB Shane Vereen. He's ranked as the 12th QB but it's really hard for me to see him fall outside the top 10 when the season comes to a close.
165. Dorial Green-Beckham, WR
There's a chance that Marcus Mariota does really well this year and Dorial Green-Beckham is the most talented receiver on the Titans.
167. Cameron Artis-Payne
There's more than a chance that RB Jonathan Stewart misses time this season (he's missed 20 games in the last 3 seasons).
171. Matthew Stafford, QB
Stafford was the 4th quarterback off the board in 2014. Now he's 14th. Last year he really slumped but we know he has top 5 upside. Plus, his offensive line is improved, he gets a healthy Calvin Johnson, Golden Tate proved himself as a high-end number 2, and Eric Ebron is likely to improve in year 2.
174. Brian Quick, WR
Before suffering a season-ending shoulder injury in week 8, Quick looked like the clear #1 receiver on the Rams. He was the #20 receiver in points per game over the first 6 games when he was healthy. Now he gets a substantial upgrade at QB from Austin Davis to Nick Foles who has been good enough to produce valuable receivers in Philadelphia (DeSean Jackson in 2013 and Jeremy Maclin in 2014).
178. Sam Bradford, QB
Combine the 2 Eagles QBs last year, and you get the #13 QB in fantasy (just 23 points less than Matt Ryan, the #7 QB). Chip Kelly's offense produces big stats at the QB position and Bradford is potentially much better than either Foles or Sanchez. He's a potential top 10 QB.
195. Devin Funchess, WR
Kelvin Benjamin tore his ACL and is out for the season. Funchess will rise quickly through the ranks. His upside is about where Benjamin was last year.
196. Austin Seferian-Jenkins, TE
He's a huge end zone target and Jameis Winston is an upgrade over the QBs they had last year.
205. Chris Polk, RB
Arian Foster is out for the first half of the season and the Texans have one of the best offensive lines in the league along with one of the most favorable schedules in the league. Head coach Bill O'Brien wants to establish the run as the Texans led the league in rushing attempts in 2014 by a wide margin. Alfred Blue is, for now, the presumed starter but he's just not a good player. Whereas Arian Foster finished 5th in the NFL with 4.8 yards per carry, Alfred Blue finished dead last running behind the same line. I am reasonably confident that Polk will get a fair shot to take over at some point before Foster can get back on the field.
214. Jameis Winston, QB
You never know. He has arguably the best wide receiver duo in the league and a great schedule as well.
216. Chris Johnson, RB
I doubt it but you never know. That Arizona O-line got a lot better.
221. Eagles D/ST
The Eagles D/ST finished as the 2nd best defense in fantasy last year. So why are they ranked as the 14th defense this year? Sure, the 11 touchdowns is sure to regress a bit but the Eagles do have one of the better special teams units in the league. In addition, their front 7 is elite, finishing 2nd in the league with 49 sacks. The main weakness of the defense last year was the paper secondary but that unit has been greatly improved now that the Eagles have added CB Byron Maxwell, CB Eric Rowe, and FS Walter Thurmond.
225. Stevie Johnson, WR
He had 3 straight 1,000 yard seasons in Buffalo with Ryan Fitzpatrick at QB. Philip Rivers is by far the best QB Johnson has ever had and he could have a large role with Antonio Gates suspended for 4 games, Eddie Royal to Chicago, and Malcolm Floyd old.
247. Marcus Mariota, QB
Hey, there's a chance for upside and he's a mobile QB which is valuable for fantasy.
272. Eric Ebron, TE
He was the 10th overall pick in 2014. Maybe he'll break out in year 2.
273. Tyler Eifert, TE
Former first rounder, tremendous size (6'5", 250 lbs), and Jermaine Gresham is gone.
277. Vernon Davis, TE
Last year was bizarre. Davis was awful after finishing 2nd among tight ends in 2013. I don't know what happened last year, but he's worth considering for the chance that he returns to being elite or at least startable.